Health

Knowing about the R21 malaria vaccine that NAFDAC has approved in the interim

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malaria vaccine : The Nigerian government has received preliminary authorisation from the National Agency for Food and Drug Administration and Control, or Nafdac, to utilise the R21 malaria vaccine.

With the clearance of the vaccine that the Serum Institute of India manufactures, Nigeria will become the second nation after Ghana to do so.

The Agency’s Director General, Prof. Christianah Adeleye, further explains that the evaluation committee has determined that the vaccine is only 75% effective at preventing malaria.

She continues by saying that the vaccine’s potential benefits outweigh its possible drawbacks.

Before receiving market authorization, it is anticipated that Nigeria would receive contributions of at least 100,000 doses of the vaccine. To that end, plans have already been made with the National Primary Health Care Development Agency (NPHCDA).

To avoid clinical malaria in children between the ages of five and 36 months, she advised mothers to use the vaccination.

The vaccination must be stored between 2 and 8 °C.

Nafdac has made a commitment to ensure that only high-quality, safe, and effective items are made available to Nigerians.

One of the most significant global public health issues is malaria.

According to the WHO, Nigeria leads the globe in malaria-related fatalities.

According to the WHO’s malaria report for 2021, Nigeria has the highest rate of malaria-related fatalities worldwide.

Nigeria is responsible for 31.3% of malaria deaths globally, while the Democratic Republic of the Congo records 12.6%, according to the WHO research titled World Malaria research 2022.

Behind the United Republic of Tanzania and the Democratic Republic of the Congo, which both recorded 4.1%, Niger came in third with 3.9%.

51.9% of malaria fatalities globally occur in the one mean, four kontris.

The WHO estimates that there will be 247 million cases of malaria worldwide in 2021, and that this infection will kill an estimated 619,000 people.

According to a research that the WHO contributed, 95% of malaria infections and 96% of malaria fatalities occurred in Africa in 2021.

According to reports, children under the age of five are responsible for 80% of all malaria deaths in Africa.

In 2021, there will be more instances of malaria than there were in 2020 (245 million cases), but there will be fewer fatalities due to the disease (625,000 fewer than there were in 2020).

“Death of my pikin changed the way I treat malaria”

“Halima na was my first kid, and I gave birth to her on September 20, 2019, and she passed away on March 4, 2020. Never a day goes by that I don’t think about her.

One mother, Zahrau Mustapha, malaria vaccine who lives in Kano in northwest Nigeria, is the subject of this story.

Zahrau explained how malaria killed her 5-month-old baby Halima two years ago in an interview with BBC Pidgin.

“Becoming a doctor was Halima’s ambition when she was a child, but malaria stole her away from me.

“The most agonising part, and something I’ll never forget, was when she said she would die for my hands on the way to the hospital.”

She has already learned to siddon, and while I am at home, she and I play nicely together.

She continues by saying that Halima’s passing caused people to take additional precautions to avoid contracting malaria.

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After she passed away, “we dey quick enta and for our baby na double net for her because inside our net she get her own inside and also insecticide dey always dey now.”

Why is malaria an issue

Plasmodium parasites are what cause the acute febrile sickness known as malaria. Malaria is spread to humans through the bites of female Anopheles mosquitoes that are infected.

In fact, two of the five parasite types that cause malaria vaccine in humans are the most dangerous. They are P. vivax and P. falciparum.

The most dangerous malaria vaccine parasite is P. falciparum, which is extremely prevalent in Africa. The predominant malaria vaccine parasite outside of sub-Saharan Africa is P. vivax.

Malaria’s initial signs include a fever, headache, and chills. And these signs and symptoms often show up 10 to 15 days after the infectious mosquito bite. These symptoms are not dangerous and are challenging to identify as malaria.

If people do not treat the malaria caused by P. falciparum, they may develop severe disease and pass away in less than 24 hours.

Things to know regarding the new R21 malaria vaccine

Di R21/Matrix-M malaria vaccine, developed by the Serum Institute of India (SII) and manufactured by the University of Oxford, is just the second vaccination the world has seen in a long time for a disease that has caused unfathomable misery.

The RTS,S vaccine that the World Health Organisation approved for October 2021 follows closely on the heels of this new shot. RTS,S vaccine has been shown to reduce clinical malaria cases by 39% and severe malaria vaccine cases by 30% after four doses.

The initial step of the parasite life cycle is targeted by the R21 vaccination.

When the malaria parasite-carrying anopheles mosquito bites a victim, the parasite enters the circulation and progresses through its life cycle. The intricacy of the malaria parasite’s life cycle suggests that it will take years for a vaccine to emerge.

Additionally, the vaccine contains Novavax Matrix-M, a component that strengthens the immune system’s reaction to make the shot more effective and long-lasting.

Vaccines function by exposing an antigen, malaria vaccine which can be a fragment of a virus or bacteria that our body recognises and reacts to, to our immune cells.

Ghana became the first nation to approve the R21 gemalaria vaccination

The experimental malaria vaccine, dubbed a “world-changer” by the scientists who created it, was approved for use in Ghana as the first country.

Di vaccine is also approved for use in children between the ages of five months and three years old by Ghana’s Food and Drug Authority.

Malaria vaccine

World Health Organisation statistics and data from African nations are both being studied.

After leaving them behind for the Covid-19 vaccine deployment during the epidemic, Prof. Adrian Hill, head of the Jenner Institute at the University of Oxford, said that the African kontris dey speak say “we go decide” and that is how the vaccine was developed.

We anticipate that R21 will have a significant malaria vaccine influence on child malaria mortality in the upcoming years and will eventually help achieve the ultimate aim of eliminating malaria. throughout the continent.

This post was last modified on April 21, 2023 8:27 am

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